diff --git a/tox.ini b/tox.ini
index 4f24150b7..eb0402f6a 100644
--- a/tox.ini
+++ b/tox.ini
@@ -106,6 +106,7 @@ commands =
     # don't show hypothesis plugin info in docs, see #4602
     pip uninstall hypothesis -y
     rm -rf /tmp/doc-exec*
+    rm -rf {envdir}/.pytest_cache
     make regen
 
 [testenv:jython]