diff --git a/django/conf/project_template/project_name/wsgi.py b/django/conf/project_template/project_name/wsgi.py
index b083a0e6990..f768265b23b 100644
--- a/django/conf/project_template/project_name/wsgi.py
+++ b/django/conf/project_template/project_name/wsgi.py
@@ -15,6 +15,10 @@ framework.
 """
 import os
 
+# We defer to a DJANGO_SETTINGS_MODULE already in the environment. This breaks
+# if running multiple sites in the same mod_wsgi process. To fix this, use
+# mod_wsgi daemon mode with each site in its own daemon process, or use
+# os.environ["DJANGO_SETTINGS_MODULE"] = "{{ project_name }}.settings"
 os.environ.setdefault("DJANGO_SETTINGS_MODULE", "{{ project_name }}.settings")
 
 # This application object is used by any WSGI server configured to use this
diff --git a/docs/howto/deployment/wsgi/modwsgi.txt b/docs/howto/deployment/wsgi/modwsgi.txt
index b525255dbda..01399aa5a6a 100644
--- a/docs/howto/deployment/wsgi/modwsgi.txt
+++ b/docs/howto/deployment/wsgi/modwsgi.txt
@@ -56,6 +56,15 @@ for you; otherwise, you'll need to create it. See the :doc:`WSGI overview
 documentation</howto/deployment/wsgi/index>` for the default contents you
 should put in this file, and what else you can add to it.
 
+.. warning::
+
+   If multiple Django sites are run in a single mod_wsgi process, all of them
+   will use the settings of whichever one happens to run first. This can be
+   solved with a minor edit to ``wsgi.py`` (see comment in the file for
+   details), or by :ref:`using mod_wsgi daemon mode<daemon-mode>` and ensuring
+   that each site runs in its own daemon process.
+
+
 Using a virtualenv
 ==================
 
@@ -71,6 +80,8 @@ Make sure you give the correct path to your virtualenv, and replace
 
 .. _virtualenv: http://www.virtualenv.org
 
+.. _daemon-mode:
+
 Using mod_wsgi daemon mode
 ==========================