diff --git a/django/db/models/sql/expressions.py b/django/db/models/sql/expressions.py
index 374509914d8..284e09a49a4 100644
--- a/django/db/models/sql/expressions.py
+++ b/django/db/models/sql/expressions.py
@@ -3,12 +3,13 @@ from django.db.models.constants import LOOKUP_SEP
 from django.db.models.fields import FieldDoesNotExist
 
 class SQLEvaluator(object):
-    def __init__(self, expression, query, allow_joins=True):
+    def __init__(self, expression, query, allow_joins=True, reuse=None):
         self.expression = expression
         self.opts = query.get_meta()
         self.cols = []
 
         self.contains_aggregate = False
+        self.reuse = reuse
         self.expression.prepare(self, query, allow_joins)
 
     def prepare(self):
@@ -48,11 +49,13 @@ class SQLEvaluator(object):
             self.cols.append((node, query.aggregate_select[node.name]))
         else:
             try:
+                dupe_multis = False if self.reuse is None else True
                 field, source, opts, join_list, last, _ = query.setup_joins(
-                    field_list, query.get_meta(),
-                    query.get_initial_alias(), False)
+                    field_list, query.get_meta(), query.get_initial_alias(),
+                    dupe_multis, can_reuse=self.reuse)
                 col, _, join_list = query.trim_joins(source, join_list, last, False)
-
+                if self.reuse is not None:
+                    self.reuse.update(join_list)
                 self.cols.append((node, (join_list[-1], col)))
             except FieldDoesNotExist:
                 raise FieldError("Cannot resolve keyword %r into field. "
diff --git a/django/db/models/sql/query.py b/django/db/models/sql/query.py
index f5a477f2a35..0d79230391a 100644
--- a/django/db/models/sql/query.py
+++ b/django/db/models/sql/query.py
@@ -1099,7 +1099,7 @@ class Query(object):
             value = value()
         elif isinstance(value, ExpressionNode):
             # If value is a query expression, evaluate it
-            value = SQLEvaluator(value, self)
+            value = SQLEvaluator(value, self, reuse=can_reuse)
             having_clause = value.contains_aggregate
 
         for alias, aggregate in self.aggregates.items():
diff --git a/docs/releases/1.5.txt b/docs/releases/1.5.txt
index e26b927ae79..ca6b3acfd90 100644
--- a/docs/releases/1.5.txt
+++ b/docs/releases/1.5.txt
@@ -589,6 +589,12 @@ Miscellaneous
   :ref:`Q() expressions <complex-lookups-with-q>` and ``QuerySet`` combining where
   the operators are used as boolean AND and OR operators.
 
+* In a ``filter()`` call, when :ref:`F() expressions <query-expressions>`
+  contained lookups spanning multi-valued relations, they didn't always reuse
+  the same relations as other lookups along the same chain. This was changed,
+  and now F() expressions will always use the same relations as other lookups
+  within the same ``filter()`` call.
+
 * The :ttag:`csrf_token` template tag is no longer enclosed in a div. If you need
   HTML validation against pre-HTML5 Strict DTDs, you should add a div around it
   in your pages.
diff --git a/tests/modeltests/expressions/tests.py b/tests/modeltests/expressions/tests.py
index 99eb07e3700..ca47521ccd2 100644
--- a/tests/modeltests/expressions/tests.py
+++ b/tests/modeltests/expressions/tests.py
@@ -219,3 +219,42 @@ class ExpressionsTests(TestCase):
         )
         acme.num_employees = F("num_employees") + 16
         self.assertRaises(TypeError, acme.save)
+
+    def test_ticket_18375_join_reuse(self):
+        # Test that reverse multijoin F() references and the lookup target
+        # the same join. Pre #18375 the F() join was generated first, and the
+        # lookup couldn't reuse that join.
+        qs = Employee.objects.filter(
+            company_ceo_set__num_chairs=F('company_ceo_set__num_employees'))
+        self.assertEqual(str(qs.query).count('JOIN'), 1)
+
+    def test_ticket_18375_kwarg_ordering(self):
+        # The next query was dict-randomization dependent - if the "gte=1"
+        # was seen first, then the F() will reuse the join generated by the
+        # gte lookup, if F() was seen first, then it generated a join the
+        # other lookups could not reuse.
+        qs = Employee.objects.filter(
+            company_ceo_set__num_chairs=F('company_ceo_set__num_employees'),
+            company_ceo_set__num_chairs__gte=1)
+        self.assertEqual(str(qs.query).count('JOIN'), 1)
+
+    def test_ticket_18375_kwarg_ordering_2(self):
+        # Another similar case for F() than above. Now we have the same join
+        # in two filter kwargs, one in the lhs lookup, one in F. Here pre
+        # #18375 the amount of joins generated was random if dict
+        # randomization was enabled, that is the generated query dependend
+        # on which clause was seen first.
+        qs = Employee.objects.filter(
+            company_ceo_set__num_employees=F('pk'),
+            pk=F('company_ceo_set__num_employees')
+        )
+        self.assertEqual(str(qs.query).count('JOIN'), 1)
+
+    def test_ticket_18375_chained_filters(self):
+        # Test that F() expressions do not reuse joins from previous filter.
+        qs = Employee.objects.filter(
+            company_ceo_set__num_employees=F('pk')
+        ).filter(
+            company_ceo_set__num_employees=F('company_ceo_set__num_employees')
+        )
+        self.assertEqual(str(qs.query).count('JOIN'), 2)