diff --git a/django/contrib/admin/templates/admin/app_index.html b/django/contrib/admin/templates/admin/app_index.html
index 886bf6ca00d..727f72b190e 100644
--- a/django/contrib/admin/templates/admin/app_index.html
+++ b/django/contrib/admin/templates/admin/app_index.html
@@ -4,14 +4,16 @@
 {% block bodyclass %}{{ block.super }} app-{{ app_label }}{% endblock %}
 
 {% if not is_popup %}
-{% block breadcrumbs %}
-<div class="breadcrumbs">
-<a href="{% url 'admin:index' %}">{% translate 'Home' %}</a>
-&rsaquo;
-{% for app in app_list %}
-{{ app.name }}
-{% endfor %}
-</div>
+{% block nav-breadcrumbs %}
+  <nav aria-label="{% translate 'Breadcrumbs' %}">
+    <div class="breadcrumbs">
+      <a href="{% url 'admin:index' %}">{% translate 'Home' %}</a>
+      &rsaquo;
+      {% for app in app_list %}
+        {{ app.name }}
+      {% endfor %}
+    </div>
+  </nav>
 {% endblock %}
 {% endif %}
 
diff --git a/docs/releases/4.2.1.txt b/docs/releases/4.2.1.txt
index ffc9394daec..31747c1a23d 100644
--- a/docs/releases/4.2.1.txt
+++ b/docs/releases/4.2.1.txt
@@ -44,3 +44,6 @@ Bugfixes
 
 * Fixed a regression in Django 4.2 that caused incorrect ``ClearableFileInput``
   margins in the admin (:ticket:`34506`).
+
+* Fixed a regression in Django 4.2 where breadcrumbs didn't appear on admin
+  site app index views (:ticket:`34512`).
diff --git a/tests/admin_views/test_breadcrumbs.py b/tests/admin_views/test_breadcrumbs.py
index ee4285f9a98..87186e251ca 100644
--- a/tests/admin_views/test_breadcrumbs.py
+++ b/tests/admin_views/test_breadcrumbs.py
@@ -23,3 +23,7 @@ class AdminBreadcrumbsTests(TestCase):
     def test_breadcrumbs_present(self):
         response = self.client.get(reverse("admin:auth_user_add"))
         self.assertContains(response, '<nav aria-label="Breadcrumbs">')
+        response = self.client.get(
+            reverse("admin:app_list", kwargs={"app_label": "auth"})
+        )
+        self.assertContains(response, '<nav aria-label="Breadcrumbs">')