diff --git a/django/db/models/options.py b/django/db/models/options.py
index 64e5ff53eaa..76017fc8b52 100644
--- a/django/db/models/options.py
+++ b/django/db/models/options.py
@@ -90,6 +90,7 @@ class Options:
         "concrete_fields",
         "local_concrete_fields",
         "_non_pk_concrete_field_names",
+        "_reverse_one_to_one_field_names",
         "_forward_fields_map",
         "managers",
         "managers_map",
@@ -992,6 +993,16 @@ class Options:
                     names.append(field.attname)
         return frozenset(names)
 
+    @cached_property
+    def _reverse_one_to_one_field_names(self):
+        """
+        Return a set of reverse one to one field names pointing to the current
+        model.
+        """
+        return frozenset(
+            field.name for field in self.related_objects if field.one_to_one
+        )
+
     @cached_property
     def db_returning_fields(self):
         """
diff --git a/django/db/models/query.py b/django/db/models/query.py
index 95323b6f9b4..fcc725b3fcd 100644
--- a/django/db/models/query.py
+++ b/django/db/models/query.py
@@ -662,6 +662,15 @@ class QuerySet(AltersData):
         Create a new object with the given kwargs, saving it to the database
         and returning the created object.
         """
+        reverse_one_to_one_fields = frozenset(kwargs).intersection(
+            self.model._meta._reverse_one_to_one_field_names
+        )
+        if reverse_one_to_one_fields:
+            raise ValueError(
+                "The following fields do not exist in this model: %s"
+                % ", ".join(reverse_one_to_one_fields)
+            )
+
         obj = self.model(**kwargs)
         self._for_write = True
         obj.save(force_insert=True, using=self.db)
diff --git a/tests/one_to_one/tests.py b/tests/one_to_one/tests.py
index 3c92445af6a..65efee60744 100644
--- a/tests/one_to_one/tests.py
+++ b/tests/one_to_one/tests.py
@@ -524,6 +524,29 @@ class OneToOneTests(TestCase):
             Director._meta.base_manager_name = None
             Director._meta._expire_cache()
 
+    def test_create_reverse_o2o_error(self):
+        msg = "The following fields do not exist in this model: restaurant"
+        with self.assertRaisesMessage(ValueError, msg):
+            Place.objects.create(restaurant=self.r1)
+
+    def test_get_or_create_reverse_o2o_error(self):
+        msg = "The following fields do not exist in this model: restaurant"
+        r2 = Restaurant.objects.create(
+            place=self.p2, serves_hot_dogs=True, serves_pizza=False
+        )
+        with self.assertRaisesMessage(ValueError, msg):
+            Place.objects.get_or_create(name="nonexistent", defaults={"restaurant": r2})
+
+    def test_update_or_create_reverse_o2o_error(self):
+        msg = "The following fields do not exist in this model: restaurant"
+        r2 = Restaurant.objects.create(
+            place=self.p2, serves_hot_dogs=True, serves_pizza=False
+        )
+        with self.assertRaisesMessage(ValueError, msg):
+            Place.objects.update_or_create(
+                name="nonexistent", defaults={"restaurant": r2}
+            )
+
     def test_hasattr_related_object(self):
         # The exception raised on attribute access when a related object
         # doesn't exist should be an instance of a subclass of `AttributeError`