from io import BytesIO from django.http import FileResponse FILE_RESPONSE_HOLDER = {} def file_response(request): f1 = BytesIO(b"test1") f2 = BytesIO(b"test2") response = FileResponse(f1) response._resource_closers.append(f2.close) FILE_RESPONSE_HOLDER['response'] = response FILE_RESPONSE_HOLDER['buffers'] = (f1, f2) return response