diff --git a/src/_pytest/outcomes.py b/src/_pytest/outcomes.py
index 8f6203fd7..756b4098b 100644
--- a/src/_pytest/outcomes.py
+++ b/src/_pytest/outcomes.py
@@ -58,9 +58,14 @@ class Skipped(OutcomeException):
         msg: Optional[str] = None,
         pytrace: bool = True,
         allow_module_level: bool = False,
+        *,
+        _use_item_location: bool = False,
     ) -> None:
         OutcomeException.__init__(self, msg=msg, pytrace=pytrace)
         self.allow_module_level = allow_module_level
+        # If true, the skip location is reported as the item's location,
+        # instead of the place that raises the exception/calls skip().
+        self._use_item_location = _use_item_location
 
 
 class Failed(OutcomeException):
diff --git a/src/_pytest/reports.py b/src/_pytest/reports.py
index d2d7115b2..303f731dd 100644
--- a/src/_pytest/reports.py
+++ b/src/_pytest/reports.py
@@ -324,7 +324,12 @@ class TestReport(BaseReport):
             elif isinstance(excinfo.value, skip.Exception):
                 outcome = "skipped"
                 r = excinfo._getreprcrash()
-                longrepr = (str(r.path), r.lineno, r.message)
+                if excinfo.value._use_item_location:
+                    filename, line = item.reportinfo()[:2]
+                    assert line is not None
+                    longrepr = str(filename), line + 1, r.message
+                else:
+                    longrepr = (str(r.path), r.lineno, r.message)
             else:
                 outcome = "failed"
                 if call.when == "call":
diff --git a/src/_pytest/skipping.py b/src/_pytest/skipping.py
index c7afef5db..1ad312919 100644
--- a/src/_pytest/skipping.py
+++ b/src/_pytest/skipping.py
@@ -230,8 +230,6 @@ def evaluate_xfail_marks(item: Item) -> Optional[Xfail]:
     return None
 
 
-# Whether skipped due to skip or skipif marks.
-skipped_by_mark_key = StoreKey[bool]()
 # Saves the xfail mark evaluation. Can be refreshed during call if None.
 xfailed_key = StoreKey[Optional[Xfail]]()
 
@@ -239,9 +237,8 @@ xfailed_key = StoreKey[Optional[Xfail]]()
 @hookimpl(tryfirst=True)
 def pytest_runtest_setup(item: Item) -> None:
     skipped = evaluate_skip_marks(item)
-    item._store[skipped_by_mark_key] = skipped is not None
     if skipped:
-        skip(skipped.reason)
+        raise skip.Exception(skipped.reason, _use_item_location=True)
 
     item._store[xfailed_key] = xfailed = evaluate_xfail_marks(item)
     if xfailed and not item.config.option.runxfail and not xfailed.run:
@@ -292,19 +289,6 @@ def pytest_runtest_makereport(item: Item, call: CallInfo[None]):
                 rep.outcome = "passed"
                 rep.wasxfail = xfailed.reason
 
-    if (
-        item._store.get(skipped_by_mark_key, True)
-        and rep.skipped
-        and type(rep.longrepr) is tuple
-    ):
-        # Skipped by mark.skipif; change the location of the failure
-        # to point to the item definition, otherwise it will display
-        # the location of where the skip exception was raised within pytest.
-        _, _, reason = rep.longrepr
-        filename, line = item.reportinfo()[:2]
-        assert line is not None
-        rep.longrepr = str(filename), line + 1, reason
-
 
 def pytest_report_teststatus(report: BaseReport) -> Optional[Tuple[str, str, str]]:
     if hasattr(report, "wasxfail"):
diff --git a/src/_pytest/unittest.py b/src/_pytest/unittest.py
index 6a90188ca..719eb4e88 100644
--- a/src/_pytest/unittest.py
+++ b/src/_pytest/unittest.py
@@ -29,7 +29,6 @@ from _pytest.python import Class
 from _pytest.python import Function
 from _pytest.python import PyCollector
 from _pytest.runner import CallInfo
-from _pytest.skipping import skipped_by_mark_key
 
 if TYPE_CHECKING:
     import unittest
@@ -150,7 +149,7 @@ def _make_xunit_fixture(
     def fixture(self, request: FixtureRequest) -> Generator[None, None, None]:
         if _is_skipped(self):
             reason = self.__unittest_skip_why__
-            pytest.skip(reason)
+            raise pytest.skip.Exception(reason, _use_item_location=True)
         if setup is not None:
             try:
                 if pass_self:
@@ -256,9 +255,8 @@ class TestCaseFunction(Function):
 
     def addSkip(self, testcase: "unittest.TestCase", reason: str) -> None:
         try:
-            skip(reason)
+            raise pytest.skip.Exception(reason, _use_item_location=True)
         except skip.Exception:
-            self._store[skipped_by_mark_key] = True
             self._addexcinfo(sys.exc_info())
 
     def addExpectedFailure(